Skip to main content
. 2017 Apr 6;2(4):1321–1332. doi: 10.1021/acsomega.7b00343

Figure 4.

Figure 4

(a) SDS-PAGE analysis of OVA released from coated ZMNs. Lanes: I—OVA (20 μg), II—OVA (2 μg), III—OVA released from OVA-coated ZMNs in 1 h, and IV—OVA release post ZMN insertion into the skin for 30 min. (b) Amount of OVA released in 1 h from coated ZMNs stored under different storage conditions. (c) SDS-PAGE analysis of the stability of OVA released in 1 h from coated ZMNs. Lanes: I—OVA (20 μg) and II—OVA (2 μg). Far-UV circular dichroism (CD) spectra of OVA released from the coated ZMNs stored at 2–8 °C (d) and at room temperature (RT) (e). Force–displacement curves obtained using a texture analyzer for ZMNs stored at 2–8 °C (f), at RT (g), and at 40 °C/75% relative humidity (RH) (h) on different days. The results represent the average of three replicates. AS, accelerated storage (40 °C, 75 ± 5% RH).