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Cell viability detection by the CCK-8 assay of HK-2 cells after exposure to different concentrations of COM with various shapes for 6 h. Compared with the control group, *p < 0.05, **p < 0.01. COM-HL treatment group vs corresponding concentration of COM-HLA treatment group, COM-TL treatment group vs corresponding concentration of COM-TLA treatment group, #p < 0.05, ##p < 0.01.
