Table 3. SPR Data Showing a Higher Binding Affinity for G-Quadruplex DNA^a.

	h-telo 22-mer			duplex DNA 26-mer
ligands	KD (μM)	KA (M–1)	ΔG° (kcal/mol)	KD (μM)	KA (M–1)	ΔG° (kcal/mol)	KA h-telo 22/KA dsDNA
ALI-C3	0.84	8.7 × 106	–6.95	17.1	0.1 × 106	–6.12	87.0
BBZ-ARO	0.64	9.5 × 107	–8.12	36.6	0.6 × 106	–6.43	158.3
BBZ-AROCH2	0.26	1.4 × 106	–6.14	55.2	0.4 × 106	–6.12	3.5
BMSG-SH-3	0.27	2.7 × 106	–6.37	44.7	0.8 × 106	–6.83	4.3

^aError levels for K_A and K_D values were ±15%.