Table 6. Residue-Wise ΔG_bind Contribution of Ligands with h-telo 12-mer Quadruplex^a.

residues	ALI-C3	BBZ-ARO	BBZ-AROCH2	BMSG-SH-3
T1				–4.48
A2				–4.63
G3				–2.21
G5	–9.25	–8.56	–6.91
T6	–3.06	–1.90
G11	–5.35	–6.73	–6.79
T12	–14.47	–10.70	–10.00
T13				–2.81
A14				–10.38
G15				–12.28
G16				–5.37
G17	–3.18	–11.68	–3.37
T18		–4.72	–12.02	–1.32
T19		–6.58		–6.85
A20		–7.68		–2.40
G21				–8.62
G22		–4.72
G23	–3.96		–2.44
T24	–11.16	–10.63	–3.48

^aAll energies are in kcal mol^–1.