Table 3. Antiproliferative Activity (GI₅₀) Assays with P. falciparum and a Panel of Human Cell Lines^a.

	GI50 (μM)
molecule	P. falciparum	Jurkat	K562	HeLa	HEK293
3	0.0174 ± 0.002b	0.048 ± 0.001b	0.018 ± 0.002b	0.170 ± 0.010	0.04 ± 0.020
13	0.0221 ± 0.001b	0.127 ± 0.011b	0.061 ± 0.002b	0.119 ± 0.008	0.006 ± 0.001
11b	37.9 ± 3.8	92 ± 1.0	62.3 ± 5.8	>50	35.6 ± 1.6
12b	40.1 ± 4.3	≥100	≥100	>50	36.3 ± 1.7
11e	4.85 ± 1.3	2.84 ± 0.7	7.12 ± 0.9	115.1 ± 25.3	15.9 ± 1.13
SAHA	N.D.	N.D.	N.D.	2.84 ± 0.5	0.080 ± 0.006

^aResults are shown as mean ± SD of three independent experiments; N.D.: not determined.

^bData from ref (22).