Skip to main content
. 2017 Oct 19;2(10):6939–6957. doi: 10.1021/acsomega.7b00741

Figure 3.

Figure 3

Particle size and electrical surface charge of peptide/siRNA complexes. Hydrodynamic diameter of the linear (A) and cyclic (B) peptides/siRNA complexes at different w/w ratios. The particle size for most of the complexes at the peptide/siRNA w/w ratio of 20:1 (N/P ratios of 10.2–29.5 for modified peptides) was about 200 nm or less. ζ-Potential of linear (C) and cyclic (D) peptides/siRNA complexes at different w/w ratios. Whereas most of the linear peptides showed a steady increase in the ζ-potential with a positive value for the 20:1 peptide/siRNA w/w ratio, many cyclic peptides failed to show a similar trend, and a few reached a positive ζ-potential at the highest peptide/siRNA ratio studied in this experiment. The error bars represent the standard deviation.