Table 2. EC₅₀ Values of Anti-HCMV Activity (AD169-GFP) Displayed in Virus-Infected HFFs: Artesunic Acid (16) Compared with Five Chemically Different Quinazoline–Artemisinin Hybrids 6–10 and Their Precursors 12–14.

compound	molecular weight (g/mol)	HCMV EC50 (μM)
ganciclovira	255.23	2.60 ± 0.50
artemisinin (5)b	282.42	>10
DHAb	284.35	>10
artesunic acid (16)a	384.42	3.80 ± 0.40
12	290.15	2.01 ± 0.10
13	348.23	>10
14	335.14	0.05 ± 0.02
6	603.67	5.89 ± 1.07
7	714.64	0.86 ±0.20
8	656.60	0.65 ± 0.03
9	671.57	0.21 ± 0.12
10	613.54	0.15 ± 0.05

^aEC₅₀ values have been previously reported.⁵³

^bEC₅₀ values have been previously reported.⁵⁴