Table 1. Results from the Synthesis of P(Boc-AA-HEMA) Homopolymers and Two Block Copolymers of PEGMA and MMA Using P(Boc-Ala-HEMA) as Macro-CTA at 70 °C in DMF for 5 h.
| polymer | [M]/[CTA]/[AIBN] | conv.d (%) | Mn,GPCe (g/mol) | Đe | Mn,NMRf (g/mol) | Mn,theog (g/mol) |
|---|---|---|---|---|---|---|
| P(Boc-Ala-HEMA)14a | 25/1/0.1 | 50 | 3900 | 1.10 | 4700 | 4200 |
| P(Boc-Leu-HEMA)15a | 25/1/0.1 | 64 | 4800 | 1.18 | 5500 | 5900 |
| P(Boc-Phe-HEMA)10a | 25/1/0.1 | 60 | 4300 | 1.10 | 4200 | 6000 |
| P(Boc-Ala-HEMA)14-b-PPEGMA60b | 50/1/0.1 | 87 | 20 500 | 1.12 | 22 700 | 17 800 |
| P(Boc-Ala-HEMA)14-b-PMMA37c | 50/1/0.1 | 77 | 8200 | 1.14 | 8400 | 8500 |
a
[M]/[CTA]/[AIBN] = [Boc-AA-HEMA]/[CDP]/[AIBN], Boc-AA-HEMA = Boc-Ala-HEMA or Boc-Leu-HEMA or Boc-Phe-HEMA.
b
[M]/[CTA]/[AIBN] = [PEGMA]/[P(Boc-Ala-HEMA)-macro-CTA]/[AIBN].
c
[M]/[CTA]/[AIBN] = [MMA]/[P(Boc-Ala-HEMA)-macro-CTA]/[AIBN].
d
Calculated gravimetrically.
e
Measured by GPC.
f
Determined by 1H NMR study.
g
Mn,theo = (([monomer]/[CTA] × average molecular weight (MW) of monomer × Conv.) + (MW of CTA)).