Table 3. Variants in genes linked to cardiovascular diseases.

Variants in genes linked to cardiovascular diseases found to be significantly more common in BEB samples compared to TSI samples. The (%) values denote fraction of individuals in the sample with the allele present. The p-values and % values are averaged over $k$-mers constituting the associated sequences.

Gene	SN id	Variant type	Allele	p-value	%BEB	%TSI
APOB	rs2302515	Missense	C	1.30$\times {10}^{-12}$	29.29%	8.37%
APOB	rs676210	Missense	A	7.73$\times {10}^{-25}$	72.93%	33.08%
APOB	rs1042034	Missense	C	2.28$\times {10}^{-23}$	68.67%	31.91%
CYP11B2	rs4545	Missense	T	1.31$\times {10}^{-28}$	31.33%	0.91%
CYP11B1	rs4534	Missense	T	9.36$\times {10}^{-36}$	33.00%	0.91%
WNK4	rs2290041	Missense	T	1.53$\times {10}^{-14}$	13.24%	0.47%
WNK4	rs55781437	Missense	T	1.30$\times {10}^{-12}$	15.21%	0.91%
SLC12A3	rs2289113	Missense	T	7.40$\times {10}^{-13}$	8.14%	0.00%
SCNN1A	rs10849447	Missense	C	8.67$\times {10}^{-12}$	62.88%	39.92%
ABO	-	4 bp (CTGT) deletion	-	1.17$\times {10}^{-13}$	29.15%	10.55%
ABO	rs8176741	Missense	A	2.06$\times {10}^{-16}$	27.70%	8.45%
SH2B3	rs3184504	Missense	C	8.22$\times {10}^{-23}$	92.88%	63.87%
RAI1	rs3803763	Missense	C	1.32$\times {10}^{-12}$	75.86%	51.17%
RAI1	rs11649804	Missense	A	1.95$\times {10}^{-19}$	81.57%	52.79%