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. 2017 Sep 18;2(9):5873–5890. doi: 10.1021/acsomega.7b00892

Table 4. SAR Studies of the Linker Region of 1.

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a

Compounds were tested for activity against M. tuberculosis. MIC (in μM) is the minimum concentration required to inhibit the growth of M. tuberculosis in liquid culture. MICs of active compounds are the average of two independent experiments.

b

Toxic concentration (TC50, in μM) is the concentration required to inhibit growth of Vero cells by 50%. ND = not determined.