Table 1. Proteins Differentially Bound to COB223-Biotin-Avidin-Agarose vs COB236-Biotin-Avidin-Agarose and Recognized as Poly(A)-RNA Binding Proteins under Molecular Function Ontology Analysisa.
| COB223/COB236 enrichment fold | protein name | gene symbol |
|---|---|---|
| 17 | proliferation-associated protein 2G4 | PA2G4 |
| 7 | polypyrimidine tract-binding protein 1 | PTBP1 |
| 6 | heterogeneous nuclear ribonucleoprotein M | HNRNPM |
| 6 | protein lin-28 homolog B | LIN28B |
| 5.5 | ribonuclease 4 | RNASE4 |
| 5 | ubiquitin-conjugating enzyme E2N | UBE2N |
| 5 | poly(rC)-binding protein 1 | PCBP1 |
| COB223 only | vigilin | HDLBP |
| COB223 only | 40S ribosomal protein S20 | RPS20 |
| COB223 only | RNA-binding protein Raly | RALY |
| COB223 only | polyadenylate-binding protein 1 | PABPC1 |
| COB223 only | 40S ribosomal protein S14 | RPS14 |
| COB223 only | single-stranded DNA-binding protein, mitochondrial | SSBP1 |
a
The ratio of intensities (when detectable under both conditions) was determined from MS/MS analyses.