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(a) Schematic representation of HCT-116 colon cancer cells with or without pretreatment with hyaluronic acid followed by incubation with HA-FITC-CNPs. (b) CLSM images of HCT-116 cells pretreated with or without HA followed by incubation with HA-FITC-CNPs (green fluorescent). Nucleus was stained with DAPI (blue). Scale bar = 35 μm. (c) Flow cytometry analysis of HCT-116 cells pretreated with or without HA followed by HA-FITC-CNP treatment.
