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. 2018 May 16;3(5):5281–5290. doi: 10.1021/acsomega.8b00223

Table 1. Possible Protein Targets and Available Drugs for Blocking ZIKV Infection Spread.

  protein targets drugs references
ZIKV NS5 poymerase 7DMA, 2′-C-methylcytidin, ribavirin, favipiravir, T-1105 (13)
  virus replication niclosamide (4)
host factor Axl receptor warfarin, R428 (21,22)
    BMS-777607, PF-02341066, Janssen (65)
    RU-301, RU-302 (23)
    our new hypothesis: compounds 1–5, compounds 1′ and 2′  
  caspase-3 emricasan (4)
host factors regarding virus packaging, virus secretion, immune surveillance secretory system, immune proteins   (6671)