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. 2018 May 16;3(5):5281–5290. doi: 10.1021/acsomega.8b00223

Table 5. In Vitro Assays Used in the Potential Toxicity Prediction Based on the Trained Bayesian Models.

assay description
beta lactamase-based HSE-blax heat shock factor response element
  ARE-bla antioxidant response element
  P53-bla P53 response element
  VDR-bla vitamin D receptor
  PPAR-gamma-bla peroxisome proliferator-activated receptor gamma
  PPAR-delta-bla peroxisome proliferator-activated receptor delta
  AR-bla androgen receptor
  ER-bla estrogen receptor
  FXR-bla farnesoid X receptor
  GR-bla glucocorticoid receptor
luciferase-based TR-beta-luc thyroid receptor beta
  AhR-luc aryl hydrocarbon receptor
  AR-MDA-luc androgen receptor-responsive MDA breast cancer cell line
  ER-BG1-luc estrogen receptor-responsive ovarian adenocarcinoma BG1 cell line
various DT40 WT wild-type chicken DT40 bursal lymphoma cells
  DT40 REV3 DT40 cells with DNA polymerase (REV3) mutation
  ATAD5 ATPase family AAA domain-containing protein 5