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. 2017 Jul 25;2(7):3839–3857. doi: 10.1021/acsomega.7b00273

Figure 2.

Figure 2

Chemical structure of 1,1′-((butane-1,4-diylbis(oxy))bis(4,1-phenylene))bis(3-ethylurea) 1 identified through in silico screening of the mini-Maybridge library and ELISA screening of the NusB–NusE interaction as a 20 μM potent inhibitor of the NusB–NusE PPI. Also depicted are the four regions identified for modification and SAR generation.