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Superimposed Hα secondary chemical shifts of wild-type α-conotoxins Vc1.1, BuIA, ImI, and AuIB (black line) and their disulfide-deleted analogues (red line). The correlation coefficients (R2 score) for (A) Vc1.1 vs Vc1.1[C2H,C8F], (B) BuIA vs BuIA[C2H,C8F], (C) ImI vs ImI[C2H,C8F], and (D) AuIB vs AuIB[C2H,C8F] are 0.91, 0.23, 0.73, and 0.55, respectively.
