Table 1. Design of Different Particles Prepared in This Work.
entry | particlea | diameter/nm | spacer | dye | additional components |
---|---|---|---|---|---|
1 | NH2-PEG-NP500 | 500 | PEG | ||
2 | Cy5-PEG-NP500 | 500 | PEG | Cy5 | |
3 | Cy5-PEG2-NP500 | 500 | (PEG)2 | Cy5 | |
4 | Cy5-PEG3-NP500 | 500 | (PEG)3 | Cy5 | |
5 | Fmoc-Lys(Cy5)-NP500 | 460 | lysine | Cy5 | |
6 | Fmoc-Lys(Cy5)-NP900 | 900 | lysine | Cy5 | |
7 | Strp-Lys(Cy5)-NP1200 | 1200 | lysine | Cy5 | streptavidin |
8 | Pd(0)-Cy5-PEG-NP500 | 500 | PEG | Cy5 | Pd(0) |
9 | Pd(II)-Cy5-PEG-NP500 | 500 | PEG | Cy5 | Pd(II) |
All NPs were covalently bound to their cargo through amide bonds. PEG = 1-amino-4,7,10-trioxa-13-tridecanamine succinamyl.