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. 2018 Jun 26;3(6):6912–6930. doi: 10.1021/acsomega.8b00582

Table 4. In Vitro Synergistic Antibacterial Activity of 5u.

  MIC alone (μg/mL)
 MIC in combination (μg/mL)
    
E. coli strain 5u CIP 5u CIP FICIa mode of interaction
MRA11 1024 128 512 16 0.62 partially synergistic
MRC17 1024 128 1024 64 1.50 indifferent
MRAE33 1024 2 16 2 1.02 indifferent
a

Synergy and antagonism were defined by FICI ≤ 0.5 and >4, respectively. Partially synergistic was denoted by 0.5 > FICI < 1, and indifferent was defined by 1 < FICI ≤ 4.