Table 3. On and Off Rate Constants for Interacting SYNZIP Pairs As Determined by SPR.
in solution | immobilized | ka (1/Ms) | kd (1/s) |
---|---|---|---|
A-1 | D-2 | 5.2 × 105 | 7.8 × 10–4 |
A-2 | D-1 | 1.5 × 105 | 2.5 × 10–3 |
A-2 | D-1-3 | 1.5 × 105 | 4.0 × 10–3 |
A-2 | D-3-1 | 1.1 × 105 | 3.0 × 10–3 |
A-3 | D-4 | 4.0 × 105 | 1.4 × 10–2 |
A-4 | D-3 | 1.7 × 105 | 1.9 × 10–2 |
A-4 | D-1-3 | 3.4 × 105 | 2.5 × 10–2 |
A-4 | D-3-1 | 5.1 × 105 | 2.0 × 10–2 |
1-A | D-2 | 2.9 × 105 | 1.6 × 10–3 |
3-A | D-4 | 7.5 × 105 | 1.3 × 10–2 |
4-A | D-3 | 7.0 × 105 | 2.0 × 10–2 |
4-A | D-1-3 | 2.0 × 105 | 2.7 × 10–2 |
4-A | D-3-1 | 3.0 × 105 | 1.9 × 10–2 |
A-1-A | D-2 | 1.9 × 105 | 1.7 × 10–4 |