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. 2018 May 2;3(5):4810–4815. doi: 10.1021/acsomega.8b00156

Table 4. Binding Affinities (KD) As Determined by SPR.

  immobilized
in solution D-5, nM D-6, nM D-17, nM D-18, nM D-R34m, nM D-E34m, nM
A-1 a
A-2
A-3 15b
A-4 37b
A-5 8.4 327
A-6 36 34 000b
A-17 33 1.5
A-18 12
A-R34m 268 10
A-E34m 12
a

“–” indicates no binding observed.

b

Low signal, RU (response units) less than 50.