Table 5. On and Off Rate Constants for Interacting Zipper Pairs As Determined by SPR.
in solution | immobilized | ka (1/Ms) | kd (1/s) |
---|---|---|---|
A-3 | D-17 | 4.4 × 105 | 6.7 × 10–3 |
A-4 | D-6 | 2.5 × 105 | 9.3 × 10–3 |
A-5 | D-6 | 3.1 × 105 | 2.6 × 10–3 |
A-5 | D-18 | 8.15 × 105 | 2.8 × 10–1 |
A-6 | D-5 | 1.0 × 105 | 3.7 × 10–3 |
A-6 | D-17 | 2.4 × 103 | 8.2 × 10–2 |
A-17 | D-6 | 2.0 × 106 | 6.4 × 10–2 |
A-17 | D-18 | 5.5 × 105 | 8.2 × 10–4 |
1-A | D-2 | 2.9 × 105 | 1.6 × 10–3 |
A-18 | D-17 | 1.9 × 105 | 2.4 × 10–3 |
A-R34m | D-18 | 6.7 × 107 | 1.8 × 101 |
A-R34m | D-E34m | 4.6 × 105 | 4.7 × 10–3 |
A-E34m | D-R34m | 5.5 × 105 | 6.5 × 10–3 |