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Scheme illustration of the dsRNA loading amount per LDH NPs and the relative LDH NP number at varied LDH/dsDNA mass ratios. (A) At 2:1 to 10:1, LDH NPs have the maximum dsDNA loading with some free dsDNA; (B) at 15:1 to 30:1, LDH NPs have the maximum dsDNA loading without free dsDNA; and (C) at 40:1 to 160:1, each LDH NP loads fewer dsDNA molecules without free dsDNA.
