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Schematic illustration of (A) DNA sequences and modifications (bio-: biotinylated and -Cy3: Cy3-labeled) used in this study, (B) a reaction cell made by attaching a cover glass on a slide glass with a hole, which can contain a sample solution (70 μL), and (C) immobilization of a biotinylated probe DNA on a cover glass and kinetic parameters (kon and koff) of the hybridization with Cy3-labeled target DNAs.
