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. 2018 Apr 4;3(4):3813–3818. doi: 10.1021/acsomega.8b00184

Table 3. Mismatch Discrimination by the L and R FIT-PNA Series.

mismatch FIT-PNA
  +3L 0L –3L +3R 0R –3R
T:t 0.98a 0.90 0.81 0.62 0.70 0.75
C:t 0.53 0.52 0.54 0.61 0.52 0.55
G:t 0.72 0.75 0.73 0.41 0.33 0.40
A:c 0.56 0.63 0.68 0.53 0.48 0.40
T:c 0.86 0.74 0.80 0.48 0.45 0.56
C:c 0.65 0.75 0.97 0.48 0.49 0.45
a

All values are relative to fully matched duplex (I/If). Lower case letters denote PNA nucleobases.