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. 2018 Jan 29;3(1):1178–1186. doi: 10.1021/acsomega.7b01597

Figure 8.

Figure 8

Significant shift of the lower lip that interacts with both magnesium and the amino acid present in the active site. (A) M. jannaschii ThrB-WT with l-isoleucine, magnesium (purple sphere) and ATP-γS bound into its active site (PDB: 1H74). (B) CglThrB-WT with magnesium (purple sphere) and three phosphate/sulfate bound in the active site. The omit map of all three phosphates/sulfates is contoured to 3σ. (C) Superposition of both M. jannaschii and CglThrB-WT with both their magnesium (purple spheres) and l-isoleucine and ATP-γS from 1H74.