. 2018 Feb 28;3(2):2452–2462. doi: 10.1021/acsomega.7b01776

Table 1. Curve-Fitting Analysis of Amide I Raman Band Profile of Insulin and Its Aggregates, as Obtained at Different Time Points of Incubation^a.

	species formations
	α-helix			organized β-sheet			loose β-strand, PPII and disordered components			other disordered components (undefined components)
time (min)	peak (cm^–1)	% A	width (cm^–1)	peak (cm^–1)	% A	width (cm^–1)	peak (cm^–1)	% A	width (cm^–1)	peak (cm^–1)	% A	width (cm^–1)
0	1658	54	28	1676	9	21	1686	24	27	1630	13	25
60	1659	50	28	1676	8	19	1687	28	31	1637	14	27
120	1660	46	27	1675	12	22	1687	21	26	1644	21	35
135	1656	37	19	1673	29	20	1690	22	26	1639	12	17
160	1656	29	20	1675	41	19	1691	16	25	1639	14	20
180	1655	14	18	1674	62	18	1690	14	23	1642	10	16

Percentage of areas (% A) and the bandwidth of each fitted component band are shown.

Table 1. Curve-Fitting Analysis of Amide I Raman Band Profile of Insulin and Its Aggregates, as Obtained at Different Time Points of Incubationa.