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. Author manuscript; available in PMC: 2019 Aug 3.
Published in final edited form as: J Mol Biol. 2018 Apr 5;430(16):2293–2308. doi: 10.1016/j.jmb.2018.03.024

Figure 1.

Figure 1

Membrane fission throughout the cell. Each fission event requires significant energetic contributions from diverse protein machines. Conserved structural features and assembly properties are found in all of the fission proteins highlighted here, including hydrophobic insertions, scaffolding, and polymerization. Clathrin cage structure from Fotin et al, Nature 2004 [13]. Super-constricted dynamin helix: EMDB 2701 [14]. Endophilin N-BAR scaffold on a 28 nm-diameter membrane tube: EMDB 2007 [15]. COPII cage structure: EMDB 1232 [16].