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. Author manuscript; available in PMC: 2019 Jul 13.
Published in final edited form as: ACS Infect Dis. 2018 May 10;4(7):1114–1120. doi: 10.1021/acsinfecdis.8b00052

Table 1.

Antibacterial Activities (MIC, μg/mL)a
MRSA E. coli
AG038 AG039 AG001 AG055
Sisomicin 3 0.25 0.25 0.5 0.25
6′-(2-Hydroxyethyl)sisomicin 10 1 1 1–2 1
1-LHABA sisomicin 11 0.5 1 2 0.5
Plazomicin 4 2 2 2 2
Gentamicin 5 0.25 0.25 1–2 0.5
Tobramycin 6 0.5–1 >128 4–8 2
Apramycin 18 4 4 4 4
a

All values were determined in duplicate using twofold dilution series.