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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Ann Rheum Dis. 2018 May 3;77(8):1226–1233. doi: 10.1136/annrheumdis-2017-212935

Figure 1.

Figure 1

Bar graphs of metabolic pathways showing disease-specific differential gene expression within the glomerular compartment in the discovery cohort (A). Bar graph of pentose phosphate pathway gene expression within the tubulointerstitial compartment in the discovery cohort (B). Differences in composite gene expression were compared in the discovery cohort between hypoxia-induced factor 1-alpha (HIF-1α) glycolytic targets and HIF-1α independent glycolytic enzymes in the glomerular compartment (C). *p<0.05; **p<0.01; ***p<0.005; ****p<0.001, NS, not significant. AAV, antineutrophil cytoplasmic antibody-associated vasculitis; TCA, tricarboxylic acid.