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NR4A1 regulated the Parkin activity via CaMKII pathway. a–c Western blotting assay about the CaMKII and Parkin. KN93, the inhibitor of CaMKII was used as the negative control group which reduced the expression of CaMKII and Parkin. d, e The mitophagy activity with NR4A1 knockdown or CaMKII inhibition. f The caspase 9 activity with NR4A1 knockdown and CaMKII inhibition. *P < 0.05 vs. Ctrl group; #P < 0.05 vs. ox-LDL group
