Fig. 3.

TUDCA attenuates neuronal death after SCI. a TUNEEL staining of spinal cord from sham, sham/TUDCA, SCI, and SCI/TUDCA mice. TUNEL-positive cells (red) distributed around the lesion epicenter. Nuclei were stained by DAPI (blue). Scale bar 200 μm. b Quantification of the number of apoptotic cells from SCI and SCI/TUDCA mice normalized to total area imaged. Mean apoptotic cell counts for each group for 1–7 days. All data are presented as mean ± SEM for each group (n = 5). *p < 0.05 vs. SCI groups