Fig. 6.

Overexpression of catalase and superoxide dismutase can rescue the phenotype that is associated with UBI4 deficiency. Cell proliferation (a) and spot assays (b) of CTT1- or CTA1-overexpressing ubi4Δ cells. Cell proliferation (c) and spot assays (d) of SOD1- or SOD2-overexpressing ubi4Δ cells. RLS lifespan assay of the CTT1-, CTA1-, and SOD2-overexpressing ubi4Δ cells (e), Mean lifespans and cell counts are shown in parentheses, and N is the total number of mother cells used for the RLS assay. Statistical significance was calculated by using the Wilcoxon rank-sum test, and *p < 0.05 indicated a significant difference