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. 2018 Jul 13;9(7):778. doi: 10.1038/s41419-018-0785-5

Fig. 3. miR-192/215–Rab11-FIP2 axis affected cell growth and invasion of BGC823 and HFE145.

Fig. 3

Fig. 3

a, b, c Effect of miR-192/215 targeting Rab11-FIP2 on cell proliferation by CCK8 assays, colony formation assays, and EdU assays. The numbers of colonies containing more than 50 cells were counted. Data represent mean ± SD. The cell proliferation was examined by EdU incorporation assay at 24 h after transfection. The detection was performed at 24 h, 48 h, and 72 h. The data are reported as mean ± SD for three independent experiments. d Effect of miR-192/215 targeting Rab11-FIP2 on cell scratch assays. e Effect of miR-192/215 targeting Rab11-FIP2 on cell invasion by Boyden chamber. Morphologic comparison of cells penetrating the artificial basement membrane was also shown. Data represent mean ± SD. NC: negative control of miR; 192: miR-192; 215: miR-215; FIP2Si: siRNA Rab11-FIP2; mim: mimic; inh: inhibitor. * Means statistical significance