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. 2018 Jul 13;4(2):e000693. doi: 10.1136/rmdopen-2018-000693

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© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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BAFF is increased in primary antiphospholipid syndrome and is associated with higher adjusted global antiphospholipid syndrome scores. (A) Serum levels of BAFF in patients with PAPS as compared with SLE+APS and PAPS. (B) Correlation of serum levels of BAFF with the aGAPSS in patients with PAPS. (C) mRNA expression of BAFF in purified monocytes of patients with PAPS, SLE+APS and SLE. (D) mRNA expression of BAFF-R, TACI en BCMA in purified CD19+ B-cells in patients with PAPS, SLE+APS and PAPS. Abbreviations: aGAPSS, adjusted global antiphospholipid syndrome score; APS, antiphospholipid syndrome; BCMA, B-cell maturation antigen; GUSB, Glucuronidase Beta; HC, healthy controls; ns, not significant; PAPS, primary APS; SLE, systemic lupus erythematosus; TACI, transmembrane activator and CAML interactor.