Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jul 11;5(2):e000823. doi: 10.1136/openhrt-2018-000823

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

PMC Copyright notice

Pathophysiology of CVD risk in association with cellular and metabolic pathways may be differentially affected by specific antiretroviral agents. Individuals drugs may be involved in pathways that primarily accelerate CVD risk, are neutral or decrease that risk. Certain antiretrovirals have positive and negative influences, thereby confounding attempts at prediction of impact on CVD risk. cART, combination antiretroviral therapy; CVD, cardiovascular disease; ECM, extracellular matrix; LV, left ventricle; ROS, reactive oxygen species; TGF-β1, transforming growth factor β1; TNF, tumour necrosis factor; TRAF6, TNF receptor-associated factor 6.