Table 3.
Logistic regression analysis
Variable | OR (95% CI), P values | ||
ACS (n=252) | SA (n=112) | CAD (n=364) | |
ApoB100 IgG | 0.52 (0.31 to 0.88), 0.02 | 0.47 (0.25 to 0.89), 0.02 | 0.53 (0.33 to 0.84), 0.008 |
ApoB100 IgM | 0.58 (0.34 to 0.98), 0.04 | 0.85 (0.45 to 1.61), NS | 0.66 (0.42 to 1.06), 0.089 |
HSP60 IgG | 0.52 (0.31 to 0.88), 0.02 | 0.57 (0.3 to 1.07), NS | 0.57 (0.35 to 0.92), 0.02 |
HSP60 IgM | 0.58 (0.34 to 0.99), 0.04 | 0.61 (0.31 to 1.21), NS | 0.59 (0.36 to 0.95), 0.031 |
ApoB IgG+M | 0.45 (0.25 to 0.79), 0.01 | 0.65 (0.32 to 1.29), NS | 0.54 (0.33 to 0.89), 0.016 |
HSP60 IgG+M | 0.51 (0.28 to 0.92), 0.02 | 0.67 (0.33 to 1.39), NS | 0.59 (0.35 to 1.01), 0.052 |
ApoB+HSP60 IgM | 0.67 (0.38 to 1.16), NS | 0.51 (0.26 to 1), 0.05 | 0.51 (0.32 to 0.83), 0.007 |
ApoB HSP60 IgG | 0.44 (0.23 to 0.85), 0.014 | 0.59 (0.3 to 1.16), NS | 0.56 (0.35 to 0.91), 0.018 |
ApoB peptide | 0.11 (0.005 to 2.46), NS | 0.44 (0.01 to 15.41), NS | 0.53 (0.18 to 1.53), NS |
HSP60 peptide | 0.036 (0.002 to 0.87), 0.04 | 0.28 (0.03 to 2.73), NS | 0.44 (0.22 to 0.86), 0.016 |
ApoB+HSP60 peptide | 0.187 (0.039 to 0.88), 0.03 | 0.73 (0.28 to 1.9), NS | 0.7 (0.52 to 0.95), 0.021 |
The antibody levels were divided into tertiles. The association of the antibody level in the third tertile in comparison to the first tertile was assessed using logistic regression analysis taking age, gender, body mass index (BMI), waist-hip ratio (WHR), current smoking, hypertension and diabetes as covariates.P value <0.05 was considered significant.
ACS, acute coronary syndrome; ApoB, apolipoprotein B; CAD, coronary artery disease; HSP, heat shock protein; NS, not significant; SA, stable angina.