Table 2.
Predicted Change in Percent Emphysema Over 10 Years for Participants Taking Aspirin Regularly Compared With Those Not Taking Aspirin, With and Without Propensity-Score Weighting
| Model | Change in Percent Emphysema Over 10 Years (95% CI) | P Value |
|---|---|---|
| Unweighted | ||
| Unadjusted | –0.42 (–0.70 to –0.14) | .003 |
| Model 1 | –0.35 (–0.62 to –0.09) | .009 |
| Model 2 | –0.36 (–0.63 to –0.10) | .007 |
| Model 3 | –0.34 (–0.60 to –0.08) | .011 |
| Weighted by propensity score | ||
| Unadjusted | –0.35 (–0.62 to –0.09) | .009 |
| Model 1 | –0.33 (–0.58 to –0.08) | .010 |
| Model 2 | –0.33 (–0.58 to –0.08) | .009 |
| Model 3 | –0.31 (–0.56 to –0.06) | .014 |
Model 1: Adjusted for baseline age, sex, race/ethnicity, sex × time and race/ethnicity × time interactions, education, time-varying height, weight, CT scanner model, milliamperes, and voxel size.
Model 2: Additionally adjusted for baseline pack-years, pack-years × time interaction, and time-varying cigarettes per day for current smokers.
Model 3: Additionally adjusted for baseline hypertension, C-reactive protein levels, sphingomyelin levels, ACE inhibitor or ARB use, and ACE-inhibitor or ARB use × time interaction.
See Table 1 legend for expansion of abbreviations.