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. 2018 Jul 13;19:181. doi: 10.1186/s12882-018-0979-1

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© The Author(s). 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Comparison between Wild-Type Claudin 16 (cyan ribbons) and L116 V mutant (green ribbons). The conserved W/LW motif of the Claudin family (Trp99, Leu116, and Trp117 in Claudin 16) is shown as sticks