Table 1.
DEC infection types | DEC pathotypes | Genes | DEC infection in children (n = 45) | DEC infection in adults (n = 18) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gender | Age in months (median* (IQR) − 12 (5.25–24)) | Gender | Age in years (mean [± SD] − 44.74 [±15.24]) | ||||||||||||
Male | Female | 0–12 | 13–24 | 25–36 | 37–48 | 49–60 | Male | Female | 18–24 | 25–36 | 37–48 | 49–85 | |||
Single DEC infection | Typical EPEC | eaeA and bfpA | 2 | 1 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Atypical EPEC | eaeA | 3 | 2 | 2 | 2 | 1 | 0 | 0 | 1 | 3 | 0 | 1 | 1 | 2 | |
bfpA | 5 | 8 | 7 | 6 | 0 | 0 | 0 | 5 | 1 | 0 | 1 | 3 | 2 | ||
ETEC | lt&st | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 1 | 1 | 1 | |
lt | 2 | 4 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
st | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | ||
EAEC | aggR | 3 | 2 | 2 | 3 | 0 | 0 | 0 | 1 | 1 | 0 | 2 | 0 | 0 | |
EIEC | ial | 0 | 3 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
STEC | stx1 | 4 | 0 | 2 | 2 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | |
DEC Co-infection | Atypical EPEC + Atypical EPEC | eaeA + bfpA | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
EAEC + EIEC | aggR + ial | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
Atypical EPEC + STEC | bfpA + stx1 | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
EPEC/ETEC (Hybrid DEC Strain) + atypical EPEC | eaeA/bfpA/lt + bfpA | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | |
Hybrid DEC infection | EAEC/EPEC | aggR/bfpA | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
EAEC/EIEC | stx1/ial | 1 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
Total | 25 | 20 | 21 | 20 | 1 | 1 | 2 | 12 | 6 | 1 | 5 | 5 | 7 | ||
(n = 45; p value ≤ 0.01) | (n = 18; p value ≤ 0.01) |
DEC diarrhoeagenic E. coli, EPEC enteropathogenic E. coli, ETEC enterotoxigenic E. coli, EAEC enteroaggregative E. coli, STEC Shiga toxin-producing E. coli, EIEC enteroinvasive E. coli, NTEC necrotoxigenic E. coli, CDEC cell-detaching E. coli, IQR interquartile range, SD stranded deviation
*Age expressed in median (non-normally distribution)