Table 5.
Correlation between phenotypic and genotypic resistance pattern of the DEC isolates (n = 67)
| Antimicrobial class | Antimicrobials | AMR genes detected | Pattern 1 | Pattern 2 | Pattern 3 | Pattern 4 |
|---|---|---|---|---|---|---|
| Quinolones | Ciprofloxacin and levofloxacin | qnrB, qnrS, aac(6′)-Ib | 13 (19.4%) | 20 (29.8%) | 9 (13.4%) | 25 (37.3%) |
| Aminoglycosides | Amikacin and gentamicin | aac3, aadB | 42 (62.6%) | 9 (13.4%) | 9 (13.4%) | 7 (10.29%) |
| Tetracycline | Tetracycline | tetA, tetB. tetD | 25 (37.3%) | 13 (19.4%) | 18 (23.8%) | 11 (16.4%) |
| Phenicols | Chloramphenicol | cat1 | 44 (65.6%) | 6 (8.9%) | 12 (17.9) | 5 (7.4%) |
| β-lactam | Ceftazidime, ceftriaxone, and cefoperazone-sulbactam | blaCTX, blaTEM, blaSHV | 15 (22.5%) | 16 (23.8%) | 13 (19.4%) | 23 (34.3%) |
| Trimethoprim and sulfonamide | Co-trimoxazole | sul1, sulII, sulIII, dhfr1 | 9 (13.4%) | 1 (1.4%) | 28 (41.7%) | 29 (43.2%) |
Pattern 1: No resistance gene(s) detected and phenotypically sensitive
Pattern 2: No resistance gene(s) detected but phenotypically resistant
Pattern 3: Resistance gene(s) detected but phenotypically sensitive
Pattern 4: Resistance gene(s) detected and phenotypically resistant