Fig. 4.

DCX mRNA expression data. a Significant DCX temporally differential expression between periods on temporal cortex (p value: 4.5e-¹¹³) [21]. Periods 1: Embryonic, 2: Early Fetal, 3: Early midfetal 4: Late midfetal- 5 Late fetal 6 Neonatal and early Infancy 7 Late infancy 8 Early childhood 9 Middle and Late adulthood 10:Adolescence 11: Young adulthood 12: Middle adulthood 13: Late adulthood b DCX expression on right (R) and left (L) temporal cortex on patients with temporal lobe epilepsy (TLE) [22] and controls [21] after correcting for batch differences. Periods 10, 11 and 12 c) DCX mRNA expression data from 83 TLE (divided into cases with or without temporal lobe sclerosis (TS) (neuronal loss from the superficial neocortex in addition to hippocampal sclerosis [43]) and controls from the MRC brain bank, Edinburgh, after correcting for batch, age, gender and RIN differences. Periods 10 to 13