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Immunohistochemistry of microsatellite instability in different stages of Barrett esophagus. (A) Loss of MutL homologue 1 expression in Barrett esophagus without dysplasia; (B) positive MutS homologue 2 expression in esophageal adenocarcinoma; (C) loss of MutL homologue 1 expression in Barrett esophagus with low grade dysplasia; (D) positive MutL homologue 1 expression in Barrett esophagus without dysplasia.
