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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Clin Pharmacol Ther. 2018 Jan 17;104(3):575–583. doi: 10.1002/cpt.988

Figure 1. Treo assay in HPLC-coupled with RI detector.

Figure 1

(a) The blank plasma with no matrix effect and (b) the plasma spiked with standard Treo. (c) A patient’s sample showing Treo at 5.8 min and internal standard busulfan at 4.7 min. (d) The linearity and range from 0.5 to 10 mg/mL of Treo in human plasma and is depicted by the concentration vs. area ratio curve.