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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Clin Pharmacol Ther. 2018 Jan 17;104(3):575–583. doi: 10.1002/cpt.988

Figure 3. Influence of Treo CL and AUC on OS.

Figure 3

(a) Cox-regression analysis on the Treo CL quartiles indicates patients with high clearance >7.97 L/h/m2 (75th percentile) tended to have a better OS (P = 0.101) as shown by the Kaplan–Meier curve. (b) Cox-regression analysis on the Treo AUC quartiles shows that patients with low AUC <1,828 mg*h/L (25th percentile) tended to have a better OS (P = 0.142).