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. Author manuscript; available in PMC: 2019 Jul 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2018 Mar 1;24(7):1463–1470. doi: 10.1016/j.bbmt.2018.02.012

Table 2.

Baseline CBU characteristics

Characteristic Carlecortemcel-L Group
N=101		 DUCBT 2006–2010
N=295		 P value
N: Total NC dose ×107/kg 101 265
Median dose1 (range) 3.06
(Min 1.29 – Max 11.00)		 4.94
(Min 2.28 – Max 24.90)
N: Total CD34 ×105/kg 101 248
Median
(range)		 1.41
(Min 0.02 – Max 11739)		 2.07
(Min 0.39 – Max 9.45)
N: HLA match – minimal2 101 266
0.9
4/6 2 70 (69.3%) 182 (68.4%)
5/6 1 28 (27.7%) 78 (29.3%)
6/6 0 3 (3.0%) 6 (2.3%)
N: HLA match – maximal3 101 266
0.0001
4/6 2 70 (69.3%) 131 (49.3%)
5/6 1 28 (27.7%) 109 (41.0%)
6/6 0 3 (3.0%) 26 (9.8%)
1

Cell dose for the single unit used, or the sum of the cell doses for the two units used.

2

Minimal DUCBT HLA match: of the two UCBUs transplanted, the match of the lesser matched unit is counted, e.g., if one UCBU is 4/6 matched to the patient, and the other is 5/6 matched to the patient, then 4/6 is counted.

3

Maximal DUCBT HLA match: f the two UCBUs transplanted the match of the better matched UCBU is counted, e.g., if one unit is 4/6 matched to the patient, and the other is 5/6 matched to the patient, then 5/6 is counted.