Table 1.
Blood alcohol concentrations and somatic withdrawal signs in alcohol vapor-exposed rats (Exp. 2)
| Vapor cycle | |||||
|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | |
| BAL (mg/dL) | ND | 165.7±15.9 | 338.3±21.7 | 187.0±23.8 | 248.8±35.1 |
| Withdrawal | |||||
| Tail stiffness (%) | ND | ND | 7 (47%) | 9 (60%)a | 11 (73%)a |
| Hyper-reactivity (%) | ND | ND | 2 (13%) | 5 (33%) | 5 (33%) |
Blood alcohol concentrations during alcohol vapor exposure cycles 2–5 (top). Numbers and proportion of rats showing withdrawal signs of tail stiffness and hyper-reactivity, 24 h after termination of vapor cycles 3–5 (bottom). N = 15
BAL blood alcohol level (mg/dL), ND not determined
aSignificant proportion of rats showing tail stiffness (ps < 0.05)