Figure 1. Disconnect between alterations in dystrophin protein levels and mRNA expression for adult and aged skeletal muscle during reloading.

A, representative western blots for dystrophin protein and Ponceau‐stained membranes used for normalization from adult and aged medial gastrocnemius (MG) (B) and tibialis anterior (TA) (D) muscles over the unloading and reloading time course (TA muscle, interaction P ≤ 0.03; main effect for age and time P ≤ 0.001). Dystrophin expression was determined by RT‐qPCR over the time course in adult and aged MG (C) and TA muscles (E) (MG muscle, main effect for time and age P ≤ 0.001; TA muscle, main effect for age P ≤ 0.001). For adult and aged muscles n = 6/time point. * P < 0.05 between age groups, † P < 0.05 vs. old baseline within group, # P < 0.05 vs. adult baseline within group. Data are presented as mean ± SEM.