Table 5.
Metabolic variables included in the model | Multiple R2 | Adjusted R 2 | P value | |
---|---|---|---|---|
mRNA | ||||
PGC‐1α | PCr, [H+], glycogen, adrenaline | 0.41 | 0.28 | 0.034 |
NRF‐2 | PCr, adrenaline | 0.32 | 0.25 | 0.018 |
TFAM | PCr, [H+], glycogen, adrenaline | 0.54 | 0.45 | 0.004 |
MFN2 | PCr, adrenaline | 0.45 | 0.39 | 0.002 |
DRP1 | PCr, [H+], adrenaline | 0.46 | 0.38 | 0.005 |
SOD2 | PCr, [H+], adrenaline | 0.27 | 0.15 | 0.071 |
HO‐1 | ATP, PCr, adrenaline | 0.22 | 0.10 | 0.168 |
HSP72 | Lactate | 0.34 | 0.31 | 0.003 |
Phosphorylated protein | ||||
AMPKα | PCr, [H+], glycogen | 0.12 | −0.02 | 0.474 |
ACC | Adrenaline, glycogen | 0.19 | 0.11 | 0.114 |
CaMKII | Lactate, [H+], glycogen | 0.39 | 0.30 | 0.017 |
p38 MAPK | ATP, lactate | 0.58 | 0.54 | <0.001 |
HDAC | [H+] | 0.01 | −0.03 | 0.639 |
ATF‐2 | Lactate | 0.16 | 0.12 | 0.054 |
mRNA abbreviations are defined in Table 2. Phosphorylated protein: AMPKα, AMP‐activated protein kinase α; ACC, acetyl‐CoA carboxylase; CaMKII, Ca2+/calmodulin‐dependent protein kinase II; p38 MAPK, p38 mitogen‐activated protein kinase; HDAC, histone deacetylase; ATF‐2, activating transcription factor‐2.