Table 5.
Associations between the intake of fruit types per 100 and dialkyl phosphates metabolite concentrations on a creatinine basis (nmol/g creatinine) across pregnancy among 610 pregnant women participating in the Generation R cohort.
| Fruit intake a | Total dialkyl phosphates b | Dimethyl alkyl phosphates c | Diethyl alkyl phosphates d | |||
|---|---|---|---|---|---|---|
|
|
|
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| B (95%CI) | P | B (95%CI) | P | B (95%CI) | P | |
| Mandarin, per 100 g/d | 0.040 (−0.045 to 0.124) | 0.359 | 0.045 (−0.044 to 0.133) | 0.321 | −0.018 (−0.123 to 0.087) | 0.732 |
| Orange/grapefruit, per 100 g/d | 0.053 (0.012 to 0.094) | 0.011* | 0.057 (0.014 to 0.099) | 0.009* | 0.040 (−0.011 to 0.091) | 0.120 |
| Lemon/lime, yes | 0.031 (−0.004 to 0.065) | 0.080 | 0.028 (−0.008 to 0.064) | 0.128 | 0.044 (0.001 to 0.087) | 0.043* |
| Banana, per 100 g/d | 0.011 (−0.052 to 0.074) | 0.728 | 0.013 (−0.053 to 0.078) | 0.707 | 0.021 (−0.056 to 0.099) | 0.588 |
| Kiwi, yes | 0.021 (−0.018 to 0.059) | 0.295 | 0.004 (−0.036 to 0.044) | 0.846 | 0.079 (0.031 to 0.127) | 0.001* |
| Apple, per 100 g/d | 0.057 (0.015 to 0.099) | 0.008* | 0.065 (0.021 to 0.109) | 0.004* | 0.031 (−0.022 to 0.084) | 0.247 |
| Pear, yes | 0.016 (−0.020 to 0.052) | 0.395 | 0.011 (−0.027 to 0.049) | 0.566 | 0.025 (−0.020 to 0.070) | 0.272 |
| Mango, yes | 0.019 (−0.017 to 0.055) | 0.303 | 0.014 (−0.024 to 0.051) | 0.475 | 0.044 (−0.001 to 0.089) | 0.056 |
| Avocado, yes | −0.001 (−0.038 to 0.036) | 0.950 | −0.004 (−0.043 to 0.035) | 0.837 | −0.003 (−0.049 to 0.043) | 0.901 |
| Peach/nectarine, yes | 0.017 (−0.018 to 0.052) | 0.336 | 0.018 (−0.018 to 0.055) | 0.330 | 0.026 (−0.018 to 0.069) | 0.245 |
| Apricot, yes | 0.063 (0.018 to 0.108) | 0.006* | 0.064 (0.017 to 0.111) | 0.007* | 0.068 (0.012 to 0.124) | 0.017* |
| Plum, yes | 0.027 (−0.010 to 0.063) | 0.153 | 0.024 (−0.014 to 0.062) | 0.207 | 0.037 (−0.008 to 0.083) | 0.107 |
| Strawberry/raspberry, yes | 0.008 (−0.029 to 0.045) | 0.664 | −0.002 (−0.041 to 0.036) | 0.904 | 0.050 (0.004 to 0.096) | 0.033* |
| Grape/cherry, yes | 0.052 (0.015 to 0.088) | 0.005* | 0.054 (0.016 to 0.092) | 0.006* | 0.042 (−0.004 to 0.087) | 0.072 |
| Pineapple/melon, yes | 0.015 (−0.021 to 0.051) | 0.415 | 0.007 (−0.031 to 0.044) | 0.727 | 0.053 (0.009 to 0.097) | 0.019* |
| Canned fruit, yes | 0.005 (−0.036 to 0.046) | 0.811 | 0.003 (−0.040 to 0.046) | 0.882 | 0.028 (−0.023 to 0.079) | 0.289 |
Adjusted for energy intake, maternal age, BMI categories (> 18,5, 18,5–25, 25–30, 30+), parity categories (0,1,2+), ethnicity categories (Dutch, other-western, non-western), education categories (low, intermediate, high), household income categories (< 1200 per month, 1200–2000 per month > 2000 per month), marital status, smoking categories (no smoking during pregnancy, smoked until pregnancy was known, smoked during pregnancy), and season of urine collection (fall, winter, spring, summer).
Total dialkyl phosphates is the sum of DEDTP, DETP, DEP, DMDTP, DMTP and DMP.
Dimethyl alkyl phosphates is the sum of DMDTP, DMTP and DMP.
Diethyl alkyl phosphates is the sum of DEDTP, DETP and DEP.