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. 2018 Jun 21;10(6):1523–1533. doi: 10.18632/aging.101488

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Copyright © 2018 Ye et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY) 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Linc00472 directly inhibited miR-1496a expression. (A) The predicted binding sites between Linc00472 and miR-141 were shown. (B) The luciferase activity was detected in 293T cells. (C) qRT-PCR analysis miR-196a expression in HT-29 and HCT-116 cells transfected with pcDNA3.1 vector (Vector) or pcDNA-Linc00472 (Linc00472). (D) qRT-PCR assay was performed to detect miR-196a expression in CRC tumor tissues and adjacent normal tissues. (E) Linc00472 expression was analyzed in TCGA COAD cohort. (F) Correlation analysis between Linc00472 and miR-196a in CRC tissues from TCGA COAD dataset. *P < 0.05, ***P < 0.001.